The Cleveland Guardians (65-56) face the San Diego Padres (68-57) in the finale of their two-game interleague series at Petco Park, with first pitch at 4:10 pm ET.

The Guardians took game one 3-1 behind homers from Oscar Gonzalez and Andres Gimenez, plus an RBI single from Jose Ramirez. Aaron Civale and the bullpen combined to limit the Padres to just one run.

Betting Line:

• Padres: -158
• Guardians: +134
• Run line: Guardians +1.5 (-160)
• Over/Under: 7.5 runs

Pitching Matchup:

• Guardians: Cal Quantrill (9-5, 3.77 ERA, 1.22 WHIP)
• Padres: Blake Snell (5-6, 3.76 ERA, 1.30 WHIP)

Key Factors:

• Jose Ramirez hits .333 with a HR vs Snell
• Amed Rosario batting .297 vs lefties this season
• Padres hitters just 4-for-23 vs Quantrill
• Juan Soto (back) questionable after missing game 1
• Padres holding final wild card spot, 1 game ahead of Brewers
• Guardians leading tight AL Central race

The Guardians have a good opportunity to sweep with Quantrill on the mound, especially if Soto remains out. The Padres' offense ranks 15th in scoring (4.40 runs/game) and averages just 3.93 runs at home.

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