NFL 2021 Thanksgiving Day Betting Guide: Expert Moneyline Picks and Analysis
Here are the expert NFL moneyline picks for Thanksgiving Day 2021:
Chicago Bears @ Detroit Lions (12:30 PM ET, FOX)
- Pick: Lions ML (+135)
- Key factors: Bears dealing with coaching drama, Justin Fields out, Lions showing fight despite record
- Analysis: Detroit close to breakthrough after tie vs Steelers and close loss to Browns
- Bears missing key defensive players Khalil Mack and potentially Akiem Hicks
Las Vegas Raiders @ Dallas Cowboys (4:30 PM ET, CBS)
- Pick: Cowboys ML (-335)
- Key factors: Cowboys looking to bounce back after Chiefs loss
- Analysis: Raiders on losing skid, limited offensively without Henry Ruggs
- Cowboys have superior talent despite recent struggles
Buffalo Bills @ New Orleans Saints (8:20 PM ET, NBC)
- Pick: Bills ML (-278)
- Key factors: Saints limited offensively, Bills more talented overall
- Analysis: Bills inconsistent but should handle Saints team lacking offensive weapons
- Saints QB situation remains problematic
Parlay Option: Bills + Cowboys + Lions ML = +315 odds
Note: While spreads available, moneyline picks recommended given volatility of holiday games. Primary risks include Lions' winless record and Bills' inconsistency.
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