
Ohio State Buckeyes: Top Betting Picks and Predictions for 2022 Season
After missing the College Football Playoff in 2021 with an 11-2 record (8-1 Big Ten), the Ohio State Buckeyes enter 2022 with championship aspirations. Here are the key betting opportunities for the upcoming season:
Notre Dame vs Ohio State (Week 1):
- Ohio State -14.5 (-110)
- Strong value with home field advantage
- College Gameday atmosphere in Columbus
- Buckeyes have superior talent and experience
Championship Odds:
- Ohio State +250 to win CFP
- Third-best odds behind Alabama and Georgia
- Strong returning offense led by QB CJ Stroud
- Favorable schedule with 6 of 9 bowl opponents at home
- New defensive coaching staff addresses 2021 struggles
Heisman Trophy:
- CJ Stroud +175 (Preseason favorite)
- 2021 stats: 4,435 yards, 44 TDs, 72% completion
- Ranked 5th in yards, 3rd in TDs, 1st in QBR
- Key receivers returning:
- Jaxson Smith-Njigba
- Marvin Harrison Jr.
- Julian Fleming
The Buckeyes aim to avenge their 2021 loss to Michigan and return to the College Football Playoff behind an explosive offense and revamped defense. With experienced talent returning at key positions, Ohio State presents strong betting value across multiple markets.

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