Top MLB Parlay Picks: Yankees, Brewers, Guardians Lead September 22 Betting Slate

Top MLB Parlay Picks: Yankees, Brewers, Guardians Lead September 22 Betting Slate

By Marcus Sullivan

March 17, 2025 at 04:42 PM

Here's a concise, value-focused version of the MLB parlay article:

A loaded 13-game MLB slate tonight offers excellent parlay opportunities as playoff races intensify. Here's a strategic three-team parlay focusing on teams with playoff implications:

Milwaukee Brewers (-150) vs. Cincinnati Reds

  • Brewers are 2.5 games back in Wild Card race
  • Brandon Woodruff (11-4, 3.26 ERA) starting against Hunter Greene (4-12)
  • Brewers' superior pitching gives them clear advantage against struggling Reds

New York Yankees (-170) vs. Boston Red Sox

  • Yankees coming off 14-2 win against Pirates
  • Aaron Judge at 60 home runs for the season
  • Yankees lead Red Sox by 97 home runs this year
  • Yankees offense averaging significantly more runs than Boston

Cleveland Guardians (-135) vs. Chicago White Sox

  • Guardians lead AL Central by 6 games
  • Lead season series 11-7 against White Sox
  • Shane Bieber (11-8) starting, ranks top 15 in ERA, strikeouts, and WHIP
  • White Sox struggling with negative run differential

Key Factors:

  • All three favorites have strong starting pitching matchups
  • Teams fighting for playoff positions
  • Clear statistical advantages in each matchup

[Original image placements preserved]

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