The San Francisco 49ers (-3.5) head to Seattle to face the struggling Seahawks in a crucial NFC West matchup. The 49ers enter on a three-game win streak, while Seattle has lost six of their last seven games.

49ers Outlook:

• Won three straight games, scoring 30+ points in each
• Jimmy Garoppolo averaging 8+ yards per pass attempt in last five starts
• Coming off impressive 34-26 win over Vikings
• Offense clicking at the right time for playoff push

Seahawks Status:

• 3-8 record, playoff hopes nearly extinguished
• Lost 17-15 to Washington on Monday Night Football
• Strong defense allowing under 24 points in last six games
• Major offensive struggles, scoring just 28 points total in last three games

Keys to the Game:

• 49ers must stay focused despite Seahawks' struggles and upcoming Bengals matchup
• Seattle needs dramatic offensive improvement, especially in explosive plays
• Home field advantage could help Seahawks in division rivalry game
• Russell Wilson's performance crucial for Seattle's chances

The 49ers look to continue their momentum while the Seahawks aim to salvage their season in this divisional clash. San Francisco's balanced offense against Seattle's solid defense should make for an intriguing matchup, with the 49ers favored by 3.5 points on the road.

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