Sweet 16 2025 NCAA Tournament Betting Lines and Spreads Released

Basketball player in red jersey
Sportsbooks have released initial Sweet 16 odds for the 2025 NCAA Tournament's third round. Texas Tech opens as a 4.5-point favorite against Arkansas, while Michigan faces a 7.5-point spread against top-seeded Auburn.
Arkansas vs Texas Tech (Opening Line: TTU -4.5)
Arkansas continues their Cinderella run after defeating #7 Kansas and #2 St. John's. Texas Tech advanced by beating UNC Wilmington and Drake convincingly.
Key Matchup Factors:
- Texas Tech's superior three-point shooting (10+ per game)
- Arkansas's strong free-throw generation (20.7 attempts per game)
- Razorbacks' defensive pressure (11.8 forced turnovers per game)
Michigan vs Auburn (Opening Line: Auburn -7.5)
Michigan secured their Sweet 16 spot with wins over UC San Diego and Texas A&M, while Auburn dominated Alabama State and Creighton.
Critical Elements:
- Michigan's inside defensive presence vs. Wooden Award contender Johni Broome
- Auburn's balanced attack (36.6% from three)
- Turnover battle (Auburn ranks 5th nationally in turnover rate)
Sweet 16 Odds Update Table (DraftKings)
Game | Spread | Total |
---|---|---|
Arkansas vs Texas Tech | TTU -4.5 | 142.5 |
Michigan vs Auburn | AUB -7.5 | 148.5 |
Additional matchups and odds will be updated as they're finalized. Odds current as of March 22-23, 2025.
Texas Tech beats Drake and advances to the next round to take on Arkansas 🍿 pic.twitter.com/TOJyuYliQ3
Michigan hero Roddy Gayle Jr. does the honors of sending the Wolverines into the Sweet 16. pic.twitter.com/JGGPXTbfN8