
White Sox vs Guardians April 21: Series Finale Betting Guide and Preview
The Chicago White Sox and Cleveland Guardians face off in their series finale after Cleveland took both games of Wednesday's doubleheader. First pitch is scheduled for 1:10 p.m. at Progressive Field.
Game Details:
- White Sox (-140) vs Guardians (+117)
- Run Line: Guardians +1.5 (-140)
- Over/Under: 8 runs
Pitching Matchup:
- White Sox: Dylan Cease (2-0, 1.69 ERA, 16 K, 0.94 WHIP)
- Guardians: Zach Plesac (0-1, 1.64 ERA)
Recent Series Results:
- Game 1: Guardians won 11-1 (Jose Ramirez grand slam)
- Game 2: Guardians won 2-1
Key Players:
- White Sox: Andrew Vaughn (.310/.375/.552, 2 HR, 6 RBI)
- Guardians: Jose Ramirez (.429/.479/.881, 4 HR, 20 RBI)
Notable Matchups:
- vs Plesac: Luis Robert (5-for-10), Jose Abreu & Tim Anderson (3 combined HR in 35 AB)
The Guardians look to complete the sweep after strong pitching limited Chicago to just two runs in Wednesday's doubleheader. While Plesac has been solid, he faces a tough test against the red-hot Cease, who has been one of MLB's best starters early this season.
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