The 2025 NCAA Tournament bracket is set, with odds released for each team's chances to reach the Final Four. All four #1 seeds are favored to win their respective regions.

East Region Odds:

• Duke (#1): -115
• Alabama (#2): +475
• Wisconsin (#3): +900
• Arizona (#4): +950

Duke, with Cooper Flagg returning from injury, leads all tournament teams with the best Final Four odds. They top KenPom rankings with a +38.16 rating, significantly ahead of second-ranked Florida (+36.16).

Midwest Region Odds:

• Houston (#1): +155
• Tennessee (#2): +340
• Kentucky (#3): +850
• Gonzaga (#8): +850
• Illinois (#6): +850

Houston dominates after a 19-1 Big 12 season. Gonzaga, despite being an 8-seed, shares third-best odds and boasts nine consecutive Sweet 16 appearances.

South Region Odds:

• Auburn (#1): +110
• Michigan State (#2): +470
• Iowa State (#3): +600
• Texas A&M (#4): +1200

Notable: #11 North Carolina (+4500) shows stronger odds than higher-seeded teams, including their First Four opponent San Diego State (+24000).

West Region Odds:

• Florida (#1): -110
• Texas Tech (#3): +470
• St John's (#2): +600

The West features the tournament's only first-round favorite from a double-digit seed: #12 Colorado State (-3.5) over #5 Memphis, reflected in their Final Four odds (CSU +6500, Memphis +9000).

Duke (+350) remains the overall tournament favorite, followed closely by Florida, who secured the final #1 seed after dominating the SEC Tournament.

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